OFLOXACIN
Mechanism of action:
It inhibits the bacterial DNA synthesis, by
inhibiting DNA gyrase, which reverses the super coiling of DNA strands, the
enzyme that maintains the helical twists in DNA . Thus it kills the bacteria by
inhibiting the Synthesis.
INDICATION :
→ Typhoid
and paratyphoid fever
→ Urinary tract infection
→ Ear,
nose and throat infection
→ Respiratory
tract infection
→ Skin
and soft tissue infection
→ It
is also used in multi drug resistance tuberculosis
PREPARATION:
It usually
available in tablet and suspension such as:
Ofloxacin tablet
100mg , 200mg and 400mg
DOSE :
Adult:200-400mg
bid 5 to 10 days
ADVESE EFFECT:
CNS: somnolence,
seizures, depression, sleep disorder
GIT:nausea, ,
dry mouth, abdominal pain, disguise, pseudomembranous colitis
Mis:
anaphylaxis, chest pain, trunk pain, phlebitis.
CONTRAINDICATION:
Hypersensitivity
to fluoroquinolones
+ comments + 1 comments
Ofloxacin is an antibiotic useful for the treatment of a number of bacterial infections.Ofloxacin eye drops are used to treat eye infections such as bacterial conjunctivitis (pink eye).The eye drops work by killing the bacteria that cause the infection. It works by killing bacterial cells that cause infection.Ofloxacin eye drops manufacturer in India must offer these products at reasonable rate and in addition to this must be involved in offering best-in-class.
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